Dosing
CrCl > 80: 2-3.6 mg/kg/d IV x 3 d; after 1 wk 3.6 mg/kg/d IV x3d; repeat after 10-21 d.
CrCl 80-50:
CrCl 50-10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
Fever, abdominal pain, vomiting, and arthralgia. Reactive encephalopathy causes death in 6%.
Important drug interactions
Rants and Screeds
Pearls
Treatment of choice
Use for
Don't use for
Class
Last update 11/29/19