Infectious Disease Compendium

Ticarcillin (Ticar®)

Dosing

CrCl Formula

CrCl > 80: 3 g q 4-6 h.

CrCl 80-50: 3 g q 4 - 6 h.

CrCl 50-10: q 6 - 8 h.

CrCl < 10: 2 g q 12 h.

Hemodialysis: 3 g then 2 g q 12 h.

Peritoneal dialysis: 3 g q 12 h.

Important side effects

Anaphylaxis, coagulation abnormalities; bleeding time and platelet aggregation, convulsions, hypersensitivity reactions, hypokalemia, rash, thrombophlebitis.

Important drug interactions

Rants and Screeds

A drug of historical interest.

Pearls

Treatment of choice

Use for

Guess if you want half-assed gram-negative penicillin, I suppose you could use this. Arthritis, Cellulitis, Empyema, Endometritis, eye infections, gynecologic infections, Intraabdominal infections, Neutropenic fever, Osteomyelitis, Pneumonia, Sepsis, Sinusitis, surgical prophylaxis, UTI.

Don't use for

Class

Penicillin.

Last update 11/30/19