Dosing
CrCl > 80: see specific organism for dosing.
CrCl 80-50:
CrCl 50-10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
Important drug interactions
Rants and Screeds
Pearls
Treatment of choice
Use for
Strongyloidiasis of the intestinal tract 200 mcg/kg, single po dose, scabies, W. bancrofti, B. malayi, Loa loa and Onchocerciasis 150 mcg/kg, single po dose; retreatment interval between 3 and 12 months.
Scabies both po (200 μg/kg/dose) and topical. Topical ivermectin is probably a better option, two applications a week apart (PubMed, Pubmed).
Head Lice: A single application of 0.5% ivermectin leads to 94.9% louse-free on day 2, 85.2% louse-free on day 8 (vs. 20.8%), and day 73.8 % free on day 30 (PubMed); much better than placebo.
Don't use for
Class
Last update 11/27/19