Infectious Disease Compendium

Miltefosine

Dosing

CrCl Formula

CrCl > 80: 50 mg a day.

CrCl 80-50:

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

GI, abdominal pain, fever, headache, allergic reactions.

Important drug interactions

Lots.

Rants and Screeds

Pearls

Treatment of choice

Very expensive: $16,713 for a 28-day course.

Use for

Naegleria fowleri, Leishmania, Balamuthia and disseminated Acanthamoeba infection. Call CDC Emergency Operations Center at 770-488-7100 if you are thinking of using this drug.

Don't use for

Class

Alkylphosphocholine

Last update 11/29/19