Dosing
CrCl > 80: 200 mg three times daily for three days.
Important side effects
Constipation, headache, vomiting.
Important drug interactions
Rants and Screeds
Pearls
Shortens the duration of diarrhea by 27 hours. Precisely 27 hours. That is precision without accuracy.
Treatment of choice
Use for
Bacterial diarrhea; including Clostridium difficile and travelers diarrhea. It has no absorption.
Still, it breeds rifampin resistance in Staphylococcus aureus (PubMed).
Don't use for
Class
Last update 11/30/19