Dosing
CrCl > 80: 400 mg po q 24 h.
CrCl 80-50: 400 mg po q 24 h.
CrCl 50-10: 300 mg po q 24 h.
CrCl < 10: 400 mg po q 48 h.
Hemodialysis: no change.
Peritoneal dialysis: no change.
Important side effects
Important drug interactions
Rants and Screeds
Pearls
Treatment of choice
Second-line for N. gonorrhoea.
Use for
Anything you would use a third-generation cephalosporin for. Bronchitis, Gonorrhea, Otitis media, Pneumonia, Salmonella infections, Shigella, UTI, Whipple's disease.
Don't use for
Class
Third-generation cephalosporin.
Last update: 07/10/19