Infectious Disease Compendium

Cefmetazole

Dosing

CrCl Formula

CrCl > 80: 1 - 2 g iv q 6 - 12 h.

CrCl 80-50: 1 - 2 g iv q 12 h.

CrCl 50-10: 1 - 2 g iv q 16 - 24 h.

CrCl < 10: 1 -2 g iv q 48 h.

Hemodialysis:

Peritoneal dialysis:

Important side effects

Increase in prothrombin time.

Important drug interactions

Rants and Screeds

Pearls

Like all cephamycins, better anaerobic spectrum and stable to ESBL.

Treatment of choice

Use for

Appendicitis, Cellulitis, Cholangitis, Cholecystitis, chronic Bronchitis, Intraabdominal infections, PID, Peritonitis, Pneumonia, surgical prophylaxis (its main use), UTI.

Maybe ESBL(Pubmed)(Pubmed).

Don't use for

Class

Second-generation cephalosporin, a cephamycin.

Last update: 07/24/19