Dosing
CrCl Formula
CrCl > 80: 25 mg/kg given for 5-7 days or 30 mg/kg for 4 days po depending on pathogen.
CrCl 80-50:
CrCl 50-10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
CNS toxic.
Important drug interactions
Rants and Screeds
Pearls
Treatment of choice
Use for
Schistosomiasis. Effective against S. haematobium and S. mansoni, but less so against S. japonicum and S. intercalatum infections.
Don't use for
Class
Inhibits the phosphofructokinase enzyme
Last update 11/29/19