Dosing
CrCl > 80: 1 - 3 g q 6 - 8 h iv.
CrCl 80-50: 0.5 - 1.5. g q 8 h iv.
CrCl 50-10: 250 mg - 1 g iv q 24 h iv.
CrCl < 10: 500 mg q 24 h iv.
Hemodialysis: dose after dialysis.
Peritoneal dialysis: 3 g q 48 h iv.
Important side effects
Important drug interactions
Rants and Screeds
Pearls
No longer available in the US.
Treatment of choice
Use for
Arthritis, bacteremia, Cellulitis, Endocarditis, Escherichia coli infections, Gonorrhea, gynecologic infections, Haemophilus influenzae infections, Intraabdominal infections, Klebsiella pneumoniae infections, Meningitis, Osteomyelitis, PID, Pneumonia, Proteus indole positive infections, Providencia stuartii infections, Salpingitis, Sepsis, Serratia infections, surgical prophylaxis, UTI.
Don't use for
Class
Third-generation cephalosporin.
Last Update: 08/22/19.