Dosing
CrCl > 80: 200 mg po or iv qd.
CrCl 80-50:
CrCl 50-10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
GI upset and headache.
Has the same hematologic effects as linezolid in short course (10 d) of therapy. Tedizolid may have less gastrointestinal and hematologic side effects and does not have drug interactions with selective serotonin reuptake inhibitors compared to linezolid.
Important drug interactions
Rants and Screeds
Pearls
Treatment of choice
Use for
Approved for the treatment of cellulitis. 200 mg a day for 6 days (PubMed). Effective against most gram-positives.
Don't use for
Class
Oxazolidinone. Static.
Last update 11/30/19