Dosing
CrCl > 80: 500 mg - 2.0 g q 4 - 6 h iv.
CrCl 80-50: 500 mg - 2.0 g q 6 h iv.
CrCl 50-10: 500 mg - 2.0 g q 8 h iv.
CrCl < 10: 500 mg - 2.0 g q 12 h iv.
Hemodialysis: 7.5 - 15 mg/kg before, then q 12 h.
Peritoneal dialysis: na.
Important side effects
Important drug interactions
Rants and Screeds
Pearls
Treatment of choice
Use for
No longer used in the US for humans, evidently still available for cattle.
Cellulitis, Endocarditis, Pneumonia, Osteomyelitis, Peritonitis, preoperative prophylaxis, UTI.
Don't use for
Class
First-generation cephalosporin.
Last Update: 08/27/19.