Infectious Disease Compendium

Telavancin (Vibativ)

Dosing

CrCl Formula

CrCl > 50: 10 mg/kg every 24 h.

Important side effects

Mild taste disturbance (a tendency to wear bell-bottoms?), nausea, vomiting, serum creatinine concentration elevation.

Important drug interactions

Rants and Screeds

Pearls

VISA-Daptomycin non-susceptible Staphylococcus aureus are frequently resistant to Telavancin (PubMed).

Treatment of choice

Use for

Gram-positive organisms, including MRSA. It is equal to vancomycin (and therefore a piece of crap) for cellulitis and hospital-acquired pneumonia (pneumonia cure rates with telavancin versus vancomycin were 58.9% versus 59.5%. Ick.) (PubMed).

Don't use for

Class

Lipoglycopeptide.

Last update 11/30/19