Gram-negative Cocci/Coccobacillus
Penicillins | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
penicillin | 2 |
3 |
3 |
1 |
1 |
1 |
3 |
2 |
2 |
2 |
2 |
ampicillin/amoxicillin | 2 |
3 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
amoxicillin/clavulanate | 2 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3(?) |
3 |
ampicillin/sulbactam | 2 |
3 |
3 |
3 |
3 |
3 |
3 |
3(?) |
3(?) |
3(?) |
3(?) |
nafcillin/oxacillin /dicloxacillin | 1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
mezlocillin/ piperacillin | 2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3(?) |
3(?) |
3 |
ticarcillin/clavulanate | 2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3(?) |
3(?) |
3 |
piperacillin/tazobactam | 2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3(?) |
3(?) |
3 |
Cephlosporins | --- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
cefazolin / cephalexin | 1 |
2 |
2 |
2 |
1 |
1 |
1 |
1 |
1 |
3 |
1 |
2nd genration: eg cefuroxime | 1 |
3 |
3 |
3 |
3 |
1 |
1 |
1 |
1 |
1 |
1 |
cefotaxime / ceftriaxone | 3 |
3 |
3 |
3 |
3 |
3 |
3 |
3(?) |
3(?) |
3(?) |
3 |
ceftazadime | 3 |
3 |
3 |
3 |
3 |
3 |
3 |
3(?) |
3(?) |
3(?) |
3 |
cefepime | 3 |
3 |
3 |
3 |
3 |
3 |
3 |
3(?) |
3(?) |
3(?) |
3 |
Aminoglycosides | --- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
gentamicin / tobramycin | 2 |
2 |
2 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
amikacin | 2 |
2 |
2 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
Macrolides | --- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
erythromycin | 1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
clarithromycin | 2 |
2 |
2 |
2 |
2 |
2 |
1 |
1 |
1 |
1 |
1 |
azithromycin | 2 |
2 |
2 |
2 |
3 |
2 |
1 |
1 |
1 |
1 |
1 |
dirithromycin | 1 |
1 |
1 |
2 |
2 |
1 |
1 |
1 |
1 |
1 |
1 |
telithromycin | 1 |
1 |
2 |
3 |
3 |
1 |
1 |
1 |
1 |
1 |
1 |
clindamycin | 1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
Tetracyclines | --- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
tetracycline / doxycycline | 2 |
2 |
2 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
tigecycline | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Carbapenems | --- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
ertapenem | 3 |
3 |
3 |
3 |
3 |
3 |
3 |
3? |
3? |
3? |
3? |
meropenem | 3 |
3 |
3 |
3 |
3 |
3 |
3 |
3? |
3? |
3? |
3? |
imipenem | 3 |
3 |
3 |
3 |
3 |
3 |
3 |
3? |
3? |
3? |
3? |
Misc. | --- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
--- |
metronidazole | 1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
aztreonam | 3 |
3 |
3 |
3 |
3 |
3 |
3 |
3? |
3? |
3? |
3 |
colistin | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
rifampin | . |
prophylaxis |
. |
. |
. |
. |
. |
. |
synergy |
. |
. |
rifaximin | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
trimethoprim/sulfamethoxisole | 1 |
2 |
2 |
2 |
2 |
2 |
2 |
1 |
1 |
1 |
1 |
vancomycin | 1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
quinupristin/dalfopristin | 1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
linezolid | 1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
daptomycin | 1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
Quinolones | (8) |
1 |
|||||||||
levofloxacin | 2 |
3 |
3 |
3 |
3 |
3 |
3? |
3? |
3? |
3? |
3? |
moxifloxacin /gatifloxacin | 2 |
3 |
3 |
3 |
3 |
3 |
3? |
3? |
3? |
3? |
3? |
ciprofloxacin | 2 |
3 |
3 |
3 |
3 |
3 |
3? |
3? |
3? |
3? |
3? |
3= great. Use an antibiotic empirically if it is a 3.
2.5 = the best we got, but I sure wish we had better. OK to use empirically as we do not have any other choice.
2= adequate if susceptible, use with caution (ie know what you are doing and local susceptibility patterns) but do not rely on it empirically if you do not have susceptibilities.
1.5 = if it is susceptible its great, but is almost never susceptible.
1= no way dude. You want a dead patient?
R = resistant
"?" = looks good in a test tube
"." = placeholder pending data
Notes:
(7) Use spectinomycin.
(8) Not endocarditis.