Dosing
CrCl > 80: 0.82 mg/kg/hr inhaled. 400 mg po bid when treating Hepatitis C.
Important side effects
Anorexia, dyspepsia, nausea, cardiac arrest, hypotension, bradycardia (inhaled), conjunctivitis, headache (inhalation; health-care workers administering ribavirin), fatigue, headache, hemolytic anemia, pancreatitis, precipitation of drug within the ventilatory apparatus (inhaled), rash, pruritus, worsening respiratory status including death (inhaled).
Important drug interactions
Abacavir, didanosine, interferon alfa-2b, lamivudine, stavudine, zalcitabine, zidovudine.
Rants and Screeds
Pearls
Treatment of choice
Use for
RSV. Hepatitis C (with interferon). It gets thrown at many viral infections whether it does anything or not: hantavirus pulmonary syndrome, hemorrhagic cystitis, hemorrhagic fever, Hepatitis A, Hepatitis B, adenovirus, hepatitis C with HIV coinfection, hepatitis-giant cell, Herpes simplex infection, influenza infection, papillomatosis, pneumonia - adenovirus, severe acute respiratory syndrome (sars), subacute sclerosing panencephalitis.
Maybe for chronic Hepatitis E.
Don't use for
Class
Last update 11/30/19