Infectious Disease Compendium

Benznidazole

Dosing

CrCl Formula

CrCl > 80: 5-7 mg/kg per day orally in 2 divided doses for 60 days; only available in the US from the company.

CrCl 80-50:

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

Neuropathy and angioedema.

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

Chagas. Most effective in acute disease.

Don't use for

Class

Antiprotozoal.

Last Update 05/30/19.