Dosing
CrCl > 80: 40 mg once, if > 80 kg, 80 mg once.
Important side effects
GI Upset.
Financial: $150.
Important drug interactions
Rants and Screeds
Pearls
Patients get better about a day faster. Give within 48, or even better, 24 hours of onset of symptoms.
Treatment of choice
Use for
Influenza A and B. May be better than olsetamivir for B (PubMed). It inhibits A>B>C>D and a variety of animal influenzas (PubMed).
Class
Blocks influenza replication by inhibition of viral endonuclease.
Last Update: 08/03/19.