CrCl > 80: 600 mg IV. Usually just once and it cost a cool grand.
CrCl 30-49 mL/min: 200 mg IV as a single dose/p>
CrCl 10-29 mL/min: 100 mg IV as a single dose
Important side effects
Low wbc, increase glucose and, of course, diarrhea.
Important drug interactionsRants and Screeds
What the hell is your patient getting influenza for anyway? Haven't you heard of the vaccine, bub?
Pearls
92% of influenza is now resistant to amantadine and rimantadine; only useful if given within the first 72 hours of illness and shortens the illness by a day or so. Given how awful influenza is, it's probably worth it.
Treatment of choice
Use for
Influenza A and B.
It is no worse than oseltamivir but it costs a tonne. (PubMed).
Don't use for
Class
Neuraminidase inhibitor
Last update 11/30/19