Dosing
CrCl > 80: depends on what your treating.
CrCl 80-50:
CrCl 50-10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
Leukopenia, megaloblastic anemia, rash, Stevens-Johnson syndrome (rare).
Important drug interactions
Aurothioglucose, folic acid, lorazepam, methotrexate, sulfamethoxazole, trimethoprim, zidovudine.
Rants and Screeds
Pearls
Treatment of choice
Use for
Prophylaxis of toxoplasma and malaria.
Don't use for
Class
Last update 11/30/19