Dosing
CrCl > 80: 50 mg q d.
CrCl 80-50:
CrCl 50-10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
Eye: dryness, burning, itching, irritation and conjunctival and corneal pigmentation and skin pigmentation.
Important drug interactions
Antacids (decreases clofazimine), fosphenytoin and phenytoin (decreases fosphenytoin and phenytoin)
Rants and Screeds
Pearls
Treatment of choice
Used in the multidrug treatment of leprosy.
Use for
Don't use for
Class
Phenazine dye and interferes with DNA.
Last Update: 09/25/19.