Nifurtimox
Dosing
CrCl > 80: 8 - 10 mg/kg/d in 3 - 4 doses.
CrCl 80-50:
CrCl 50-10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
GI upset, all manner of CNS side effects: CNS excitation, depression, fatigue, headache, memory impairment, paresthesias or peripheral neuropathy, tremors, vertigo or ataxia, weakness, sleep disorders.
Important drug interactions
Rants and Screeds
Pearls
Treatment of choice
Use for
Don't use for
Class
Last update 11/29/19