Dosing
CrCl > 80: 300 mg po single dose
Important side effects
Abdominal pain, hemolytic anemia (check for G6PD deficiency, which is protective against malaria, so they are likely negative), leukopenia, methemoglobinemia.
Important drug interactions
Rants and Screeds
Pearls
Maybe not as good as primaquine: "In the intention-to-treat population, the percentage of patients who were free from recurrence at 6 months was 62.4% in the tafenoquine group, 27.7% in the placebo group, and 69.6% in the primaquine group (PubMed)(PubMed)."
Treatment of choice
The liver phase of P. vivax.
Use for
Don't use for
Class
Last update 11/30/19