Dosing
CrCl > 50: 10 mg/kg every 24 h.
Important side effects
Mild taste disturbance (a tendency to wear bell-bottoms?), nausea, vomiting, serum creatinine concentration elevation.
Important drug interactions
Rants and Screeds
Pearls
VISA-Daptomycin non-susceptible Staphylococcus aureus are frequently resistant to Telavancin (PubMed).
Treatment of choice
Use for
Gram-positive organisms, including MRSA. It is equal to vancomycin (and therefore a piece of crap) for cellulitis and hospital-acquired pneumonia (pneumonia cure rates with telavancin versus vancomycin were 58.9% versus 59.5%. Ick.) (PubMed).
Don't use for
Class
Lipoglycopeptide.
Last update 11/30/19