Infectious Disease Compendium

Eflornithine

Dosing

CrCl Formula

CrCl 80-50: 100 mg/kg iv qid 14 days, followed by 75 mg/kg/day po qid.

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

Bone marrow suppression and seizures.

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

Trypanosoma brucei gambiense aka African Sleeping Sickness, PJP.

Don't use for

Last update 11/19/19