Dosing
CrCl > 80: 3 - 4 g iv q 6 h.
CrCl 80-50:
CrCl 30-10: 2 - 3 g iv q 8 h.
CrCl < 10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
Usual.
Important drug interactions
Methotrexate.
Rants and Screeds
Pearls
Treatment of choice
Use for
An antipseudomonal penicillin, it has been supplanted by piperacillin.
Bacteremia, Bacteroides, Bites, animal and human, Cellulitis, cesarean section, Empyema, Endometritis, Escherichia coli, Gonorrhea, gynecological infections, Haemophilus, hysterectomy, Klebsiella, Lung abscess, Meningitis, Neutropenic fever, pelvic cellulitis, PID, pneumonia, Proteus, Pseudomonas, Sepsis, surgical prophylaxis, UTI.
Don't use for
Class
Penicillin.
Last update 11/29/19