Infectious Disease Compendium

Etravirine (Intelence®)

Dosing

CrCl Formula

For up-to-date information, go to http://hivinsite.ucsf.edu/.

CrCl > 80: 200 mg BID.

No change for decreased CrCl.

Important side effects

Nausea and rash.

Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, and, DRESS hypersensitivity reactions.

Important drug interactions

Potent inducer of the p50 system, avoid giving with fosamprenavir, high-dose ritonavir, atazanavir, rifampin, and antiepileptic medications.

Rants and Screeds

Pearls

Treatment of choice

Use for

HIV.

Don't use for

Class

NNRTI

Last Update 11/21/19