Dosing
For up-to-date information, go to http://hivinsite.ucsf.edu/.
CrCl > 80: Darunavir must be coadministered with ritonavir to boost levels.
Treatment naive or patients with no mutations associated with resistance to darunavir: Darunavir 800 mg QD + ritonavir 100 mg QD
Treatment experienced with ≥1 mutation associated with resistance to darunavir* Darunavir 600 mg BID + ritonavir 100 mg BID
Important side effects
Important drug interactions
Numerous.
Rants and Screeds
Pearls
Treatment of choice
Use for
HIV.
Don't use for
Class
Protease inhibitor.
Last Update: 10/30/19.