Infectious Disease Compendium

Anidulafungin (Eraxis®)

Dosing

CrCl Formula

Disseminated Candida 200-mg loading dose then 100 mg daily.

Esophageal candidiasis dose100 mg on Day 1, then 50 mg daily.

CrCl 80-50:

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

Hypotension, vomiting, headache, constipation, nausea, fever, seizures, and hypokalemia.

Important drug interactions

None.

Treatment of choice

Maybe Candida.

Use for

Candida, (maybe) Aspergillus.

Don't use for

Class

Echinocandin. Inhibits the synthesis of 1,3-beta-D-glucan

Last Update: 04/10/19.