Dosing
CrCl > 80: 50 mg a day.
CrCl 80-50:
CrCl 50-10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
GI, abdominal pain, fever, headache, allergic reactions.
Important drug interactions
Lots.
Rants and Screeds
Pearls
Treatment of choice
Very expensive: $16,713 for a 28-day course.
Use for
Naegleria fowleri, Leishmania, Balamuthia and disseminated Acanthamoeba infection. Call CDC Emergency Operations Center at 770-488-7100 if you are thinking of using this drug.
Don't use for
Class
Alkylphosphocholine
Last update 11/29/19