Dosing
For up-to-date information, go to http://hivinsite.ucsf.edu/.
CrCl > 80: 200 mg BID.
No change for decreased CrCl.
Important side effects
Nausea and rash.
Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, and, DRESS hypersensitivity reactions.
Important drug interactions
Potent inducer of the p50 system, avoid giving with fosamprenavir, high-dose ritonavir, atazanavir, rifampin, and antiepileptic medications.
Rants and Screeds
Pearls
Treatment of choice
Use for
HIV.
Don't use for
Class
NNRTI
Last Update 11/21/19