Infectious Disease Compendium

Maribavir

As of 4/11/19 not approved, but being fast-tracked

Dosing

CrCl Formula

CrCl > 400 mg po bid.

CrCl 80-50:

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

Dysgeusia: distortion of the sense of taste.

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

CMV. It is as good as ganciclovir in transplant patients with less bone marrow suppression but more gi upset (PubMed).

Don't use for

Class

Inhibits of an HCMV encoded protein kinase enzyme called UL97 or pUL97, blocking nuclear egress of viral capsids.

Last update 11/29/19