Dosing
CrCl > 80: 400 mg bid. If patients on rifampin the dose is 800 bid.
Important side effects
Low WBC, increase in transaminases and CK. Rash.
There is an association with HLA-B*53:01 and Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome (PubMed) Or should it be called DRESSS?
Important drug interactions
Rants and Screeds
Pearls
Treatment of choice
Use for
Don't use for
Class
Integrase inhibitor. Popular with Strom Thurman and George Wallace.
Last update 11/30/19